Abstract: Based on the results of greenhouse gas emission (including RCP8.5 and 4.5) from the RegCM4 over 21st century,the daily mean temperature and precipitation in Southwest China are examined in this study. The mean temperature,mean precipitation,maximum number of consecutive dry days (CDD),counts of days with precipitation> 20mm·d^-1 (R20mm), maximum 5 day precipitation total (Rx5day) and simple daily intensity index (SDII) over the 21st century are investigated and compared with respect to the period of 1986~2005,respectively. Qualitative assessments are further provided to demonstrate the changes in geological disaster over Southwestern China under the influences of future climatic variation. It is indicated that the possibility of the geological disaster in Southwest China tends to increase in the future due to the changes in the mean temperature,mean precipitation,consecutive dry,heavy precipitation,precipitation concentration and daily precipitation intensity. Nevertheless,the causes and influences depend on the different regional conditions. On the other hand,more geological disasters can be expected if the greenhouse gas concentration becomes higher since it leads to larger variability ranges of the mean temperature,mean precipitation and extreme precipitation indices in comparison to those during the period of 1986~2005.