Abstract: Based on the meteorological observation data from 1971 to 2020, this paper analyzes the forest therapy index with the methods of literature research, expert scoring and analytic hierarchy process (AHP) and calculates the comprehensive index of human comfort in various regions with the method of fuzzy analytic hierarchy process (FAHP), so as to carry out regionalization analysis of forest therapy district in Panxi Area. The results show that: Xichang, Dechang, Ningnan, Panzhihua, Renhe, Miyi and Yanbian along the Anning River are the most suitable counties for forest therapy and cold avoidance in winter, which making them the first choice for old-age care, post-disease rehabilitation and disease recuperation. The western, northern and eastern parts of the Panxi region have a high level of human body comfort in the summer half year and are colder in the winter half year. The central and southern parts are comfortable throughout the whole year, they are warm, sunny, comfortable as well as livable in winter.