Abstract: Based on the biological characteristics of Toona sinensis and the requirements of modern high-yield cultivation techniques, by using the meteorological data of 15 meteorological stations in Dazhou and its surrounding areas and domestic toona sinensis producing areas and GIS data, the climate ecological suitability of Toona sinensis in Dazhou was comprehensively analyzed. The climate ecological regionalization indexs were selected, the spatial model of climate factors was established, and the ecological climate regionalization of Toona sinensis cultivation based on GIS was developed by using the optimization method. The results showed that the climatic and ecological conditions in Dazhou were generally suitable for the growth of Toona sinensis, and the main factors affecting its cultivation were the average annual temperature and site conditions. The temperature level and accumulated temperature at the end of winter to the beginning of spring were the main climatic factors affecting the time to market and the yield of Toona sinensis, for the first stubble Toona sinensis bud harvest, the effective accumulated temperature ≥10.0℃ was about 60~70℃·d. The suitable cultivation area of Toona sinensis was mainly distributed in the central and southern part of Dazhou, accounting for 58.7% of the total area, among them, the most suitable area was mainly distributed in the subtropical middle-shallow hilly and flat area with an altitude of less than 500m and an average annual temperature of more than 16.0℃, the suitable area was mainly distributed in the low mountain and high hilly region from the north subtropical zone to the montane warm temperate zone with an altitude of 500~800m and an average annual temperature of 14.0~16.0℃. The sub-suitable zone is mainly distributed in the northern the semi-mountainous area of mountainous warm temperate zone with an altitude of 800~1200m and an average annual temperature of 12.0~14.0℃, accounting for about 26.2% of the total area. The middle and high mountain areas in the north with an altitude of more than 1 200m are unsuitable areas, accounting for about 15.1% of the total area. The middle-shallow hilly and flat area in the south of Dazhou is the key development area of Toona sinensis, the low-hilly and high-hilly area in the middle and south of Dazhou is the moderate scale development area, and the low-middle mountainous area in the north is the natural ecological distribution area.